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Researchers uncover key cancer-promoting gene

Researchers uncover key cancer-promoting gene

Published on 1/7/15

January 6, 2015 - University of Michigan Health System - One of the mysteries in cancer biology is how one protein, TGF-beta, can both stop cancer from forming and encourage its aggressive growth. Now, researchers have uncovered a key gene that may explain this paradox and provide a potential target for treatment.

Genome wide expression changes in vascular tissue identified due to infection diet

Genome wide expression changes in vascular tissue identified due to infection diet

Published on 1/7/15

Although it has been shown that a diet high in fat and exposure to certain bacteria can cause atherosclerosis, researchers have for the first time identified distinct gene pathways that are altered by these different stimuli. These findings suggest that future therapies for this disease may need to be individualized.

Novartis taps into gene editing for next generation drugs

Novartis taps into gene editing for next generation drugs

Published on 1/7/15

Novartis is diving deeper into the world of gene-based medicine by signing deals with two U.S. biotech companies, giving it access to a powerful new genome editing technology. The tie-ups with unlisted Intellia Therapeutics and Caribou Biosciences show the Swiss drugmaker's confidence in the potential of so-called CRISPR technology, both for making new medicines and as a research tool.


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